Source: https://guthlabs.ai/docs/instruments/genetic-linkage-recombination-frequency-calculator/implementation/

instrument implementation / implementation-contract

# Genetic Linkage / Recombination Frequency Calculator implementation

A source-bound implementation contract for Genetic Linkage / Recombination Frequency Calculator; deployment and executable qualification remain separate.

Status: **VERIFIED_CLEAN**Lifecycle: **implementation-contract**

## Binding contract

This record describes what an executable surface must bind and validate. It does not claim that a public calculator, package, or production route is deployed.

**Record owner**: Guth Instruments

**Lifecycle**: verified-clean

**Evidence ID**: t5-125

**Effect**: Computation or source lookup only

## Input and validation requirements

The specification has a definite undefined-result trap when total_offspring=0. It also permits plain arithmetic above the classical 50% two-point mapping limit unless the instrument separately validates or warns, producing a formally computable but biologically invalid classical estimate.

## Required corrections

No binding erratum is attached to this unique-name record. Implementers must still preserve the declared units, domain, and failure behavior.

## Inspectable interface fixture

The sample below is evidence for interface and validation tests, not a production implementation.

````
{
  "inputs": {
    "recombinant_count": 37,
    "total_offspring_count": 412
  },
  "expected_outputs": {
    "recombination_frequency_percent": 8.9805825243,
    "map_distance_cM_RF_approximation": 8.9805825243
  },
  "working": "RF fraction = 37 ÷ 412 = 0.089805825243...; RF percent = 0.089805825243... × 100 = 8.9805825243...%; naive RF-based map distance = 8.9805825243... cM."
}
````

## Other records

[01**Overview**](<https://guthlabs.ai/docs/instruments/genetic-linkage-recombination-frequency-calculator/>)[02**Mechanism**](<https://guthlabs.ai/docs/instruments/genetic-linkage-recombination-frequency-calculator/mechanism/>)[04**Qualification**](<https://guthlabs.ai/docs/instruments/genetic-linkage-recombination-frequency-calculator/qualification/>)

## Sources and evidence

These pointers bind the page to evidence. They do not grant authority or collapse verification into deployment.

- `VERIFIED_LEDGER.json`

- `evidence-tranche5/tranche5-results.json`
