Source: https://guthlabs.ai/docs/instruments/loading-maintenance-dose-calculator/implementation/

instrument implementation / implementation-contract

# Loading & Maintenance Dose Calculator implementation

A source-bound implementation contract for Loading & Maintenance Dose Calculator; deployment and executable qualification remain separate.

Status: **VERIFIED_CLEAN**Lifecycle: **implementation-contract**

## Binding contract

This record describes what an executable surface must bind and validate. It does not claim that a public calculator, package, or production route is deployed.

**Record owner**: Guth Instruments

**Lifecycle**: verified-clean

**Evidence ID**: t4-062

**Effect**: Computation or source lookup only

## Input and validation requirements

The extreme-magnitude vector produces Infinity for both outputs under plain JavaScript arithmetic. The instrument should reject non-finite inputs or outputs rather than display Infinity as a usable educational dose. The specification also contains no actual formula branch, so an implementation inventing a threshold-based branch would be unsupported.

## Required corrections

No binding erratum is attached to this unique-name record. Implementers must still preserve the declared units, domain, and failure behavior.

## Inspectable interface fixture

The sample below is evidence for interface and validation tests, not a production implementation.

````
{
  "inputs": {
    "target_concentration": "10 mg/L",
    "Vd": "35 L",
    "clearance": "4.2 L/h",
    "dosing_interval": "12 h"
  },
  "expected_outputs": {
    "loading_dose": "350 mg",
    "maintenance_dose_per_interval": "504 mg",
    "maintenance_rate": "42 mg/h"
  },
  "working": "Loading dose = 10 mg/L × 35 L = 350 mg. Maintenance dose = 10 mg/L × 4.2 L/h × 12 h = 42 mg/h × 12 h = 504 mg. Maintenance rate = 10 mg/L × 4.2 L/h = 42 mg/h."
}
````

## Other records

[01**Overview**](<https://guthlabs.ai/docs/instruments/loading-maintenance-dose-calculator/>)[02**Mechanism**](<https://guthlabs.ai/docs/instruments/loading-maintenance-dose-calculator/mechanism/>)[04**Qualification**](<https://guthlabs.ai/docs/instruments/loading-maintenance-dose-calculator/qualification/>)

## Sources and evidence

These pointers bind the page to evidence. They do not grant authority or collapse verification into deployment.

- `VERIFIED_LEDGER.json`

- `evidence-tranche4/tranche4-results.json`