HOMA-IR Insulin Resistance Index (education)

Inspectable records

Ledger state

The current ledger marks this instrument verified clean within the source-bound verification corpus.

Area

Biology, Medicine & Pharmacology (educational estimates only — every panel labeled not-medical-advice)

Tranche

tranche-5

Evidence ID

t5-088

Ledger rows

1

No ledger note is attached.

Review findings

The formula is the standard conventional HOMA-IR formula for fasting glucose in mg/dL and fasting insulin in µU/mL. The honest-label text is appropriate, but the specification needs explicit, enforceable input units and a defined fasting condition before it can receive PASS.

Formula and scope findings

No additional record

Unit assumptions

• Fasting glucose must be supplied in mg/dL.
• Fasting insulin must be supplied in µU/mL (numerically equivalent to µIU/mL).
• The divisor 405 is the conventional approximation for glucose in mg/dL and insulin in µU/mL; if glucose is in mmol/L, use the equivalent divisor 22.5 or convert glucose to mg/dL first.
• Both measurements are assumed to be obtained under fasting conditions, but the required fasting duration is not specified or enforceable by the input schema.

Boundary hardening

BREAK_CLAIMED · SELF_FLAGGED

Finite JavaScript inputs of 1e308 for both variables overflow during multiplication and produce Infinity rather than a finite HOMA-IR value. The specification also provides no stated validation for physiologically impossible zero or negative measurements and no unit-conversion guard beyond naming mg/dL.

Errata and corrections

No applied erratum is attached to this unique-name record.

Inspectable example

4 review vectors are recorded. One source-bound sample is shown below.

{
  "inputs": {
    "fasting_glucose_mg_dL": 90,
    "fasting_insulin_uU_mL": 10
  },
  "expected_outputs": {
    "homa_ir": 2.2222222222
  },
  "working": "HOMA-IR = (90 × 10) / 405\n= 900 / 405\n= 20 / 9\n= 2.2222222222"
}

Related workflows

No source-defined multi-instrument workflow membership is recorded.

Sources and evidence

These pointers bind the page to evidence. They do not grant authority or collapse verification into deployment.

• VERIFIED_LEDGER.json · VERIFIED_CLEAN
• evidence-tranche5/tranche5-results.json
• BOUNDARY_HAZARD_CATALOG.json