eGFR (MDRD, legacy) implementation

Binding contract

This record describes what an executable surface must bind and validate. It does not claim that a public calculator, package, or production route is deployed.

Record owner

Guth Instruments

Lifecycle

verified-clean

Evidence ID

t4-026

Effect

Computation or source lookup only

Input and validation requirements

The formula has undefined or non-physiologic boundary inputs that require validation: age = 0 produces an infinite mathematical result, negative serum creatinine produces an undefined real power, and an unspecified creatinine unit can produce an orders-of-magnitude error.

Required corrections

No binding erratum is attached to this unique-name record. Implementers must still preserve the declared units, domain, and failure behavior.

Inspectable interface fixture

The sample below is evidence for interface and validation tests, not a production implementation.

{
  "inputs": {
    "age_years": 60,
    "sex": "male",
    "serum_creatinine_mg_dL": 1
  },
  "expected_outputs": {
    "eGFR_mL_min_1_73m2": 76.22
  },
  "working": "SCr^-1.154 = 1.0^-1.154 = 1.000. Age^-0.203 = 60^-0.203 ≈ 0.43555. Male multiplier = 1.000. eGFR = 175 × 1.000 × 0.43555 × 1.000 = 76.22 mL/min/1.73 m²."
}

Other records

Sources and evidence

These pointers bind the page to evidence. They do not grant authority or collapse verification into deployment.

• VERIFIED_LEDGER.json
• evidence-tranche4/tranche4-results.json